Video Conference Programme
New Perspectives in Signal Transduction: GPCRs and Beyond
2nd Meeting of COST Action CA18133 ERNEST, March 2020 - Online Meeting
Conference Recordings are found here!
Program and Abstracts:
| ernest_istanbul_2020_online_program_abstracts.pdf |
Time (CET) |
Events - Day 1 |
9:00 - 9:45 |
Opening and Announcements Ibrahim Yaman, Necla Birgul, Martha Sommer Attendees: 166 |
10:00 - 10:45 |
Keynote talk (chair: Martha Sommer) Michel Bouvier (University of Montreal) Detecting and analyzing functional selectivity and biased signalling, historical perspective and potential for drug discovery Attendees: 203 |
10:45 - 11:15 |
BREAK (30 min) |
11:15 - 12:05 |
SESSION 1 WG1 (chair: Milka Vrecl) 11:15-11:35 Martha Sommer (Charité Medical University Berlin) Dynamic versatility of arrestin in GPCR and membrane binding Short talks (selected from abstracts) 11:35 - 11:50 Daniel Hilger (Philipps-University Marburg) Structural insights into differences in G protein activation by Family A and Family B GPCRs 11:50 - 12:05 Gemma Navarro (University of Barcelona ) Functional pre-coupled complexes of receptor heteromers and adenylyl-cyclase Attendees: 135 |
12:05-12:30 |
BREAK (25 min) |
12:30 - 13:00 |
SESSION 2 Poster Flash Talks 1 to 10 (10 x 3 min) Attendees: 146 |
13:00 - 14:30 |
BREAK (90 min) |
14:30 - 15:30 |
SESSION 3 Short Talks (chair: Fabrizio Fierro) 14:30 - 14:45 Johanna K. S. Tiemann (University of Copenhagen) Formation of a β2AR*-GsGDP intermediate complex 14:45 - 15:00 Thor Møller (University of Copenhagen) Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and b-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells 15:00 - 15:15 Aleksandra Luginina (Moscow Institute of Physics and Technology) δ-branch of class A GPCRs: structural aspects of activation 15:15 - 15:30 Pedard Martin (Normandie University) The urotensin II G protein-coupled receptor relays key neurobiological mechanisms in subarachnoid hemorrhage through a Gq-dependent pathway Attendees: 153 |
15:30 - 15:45 |
BREAK (15 min) |
15:45 - 17:15 |
SESSION 4 GPCRdb / GPCRmd satellite meeting (organizers: Jana Selent and David Gloriam) 15:45 - 16:30 GPCRdb (Albert Kooistra, Christian Munk, Stefan Mordalski, Kasper Harpsøe, University of Copenhagen) · Demo-session (www.gpcrdb.org) · Questions and user-implementation wishes 16:30 - 17:15 GPCRmd (Jana Selent) · Demo-session (www.gpcrmd.org) · Updates on objectives and call for contributions Attendees: 137 |
17:15 - 18:00 |
BREAK (45 min) |
18:00 - 20:00 |
SESSION 5 Social event - meeting up in virtual rooms Attendees: 78 |
ATTENTION! |
Daylight saving / summer time begins at 02:00 March 29. Clocks move ahead ONE HOUR. Don't be late for tomorrow's first session! |
Time (CET) |
Event - day 2 |
ATTENTION |
Daylight saving / summer time begins at 02:00 March 29. Clocks move ahead ONE HOUR. Don't be late for the first session! |
9:00 - 10:30 |
SESSION 6 WG2 (chair: Necla Birgul & Nina Vardjan) 9:00-09:20 Miriam Stoeber (University of Geneva) Biosensors reveal ligand-selective patterns of opioid receptor activation 9:20-9:40 Graham Ladds (University of Cambridge) Systems analysis of G protein-coupled receptor pharmacology 9:40-10:00 Ines Liebscher (University of Leipzig) The force within – Mechano-sensitive adhesion GPCR shape physiology Short talks (selected from abstracts) 10:00-10:15 Hélène Castel (Normandie University) Chemokine GPCRs function with different G proteins or anchoring partners to control glioma invasiveness 10:15-10:30 Aida Shahrakia (Bogazici University) In silico and in vitro Approaches to Characterize a Novel G-Protein Coupled Receptor in Thaumetopoea pityocampa Attendees: 133 |
10:30 - 11:20 |
BREAK (50 min) |
11:20 - 12:45 |
SESSION 7 WG3 (chair: Masha Niv & Fabrizio Fierro) 11:20-11:40 Christa Müller (University of Bonn) Tools and drugs for G proteins and G protein-coupled receptors 11:40-12:00 Leigh Stoddart (University of Nottingham) Ligand-directed affinity labelling - a new approach to visualise GPCRs Short talks (selected from abstracts) 12:00 - 12:15 Giulia Morra (Istituto di Scienze e Tecnologie Chimiche) Investigating functional selectivity in and around GPCRs with Molecular Dynamics 12:15 - 12:30 Pierre Matricon (Uppsala University) Design of a GPCR agonist by Targeting a Binding Site Water Network 12:30 - 12:45 Vigneshwaran Namasivayam (University of Bonn) Computational approaches for the proinflammatory lipid-activated G protein-coupled receptor GPR84 providing structural insights Attendees: 173 |
12:45 - 13:30 |
BREAK (45 min) |
13:30 - 14:00 |
SESSION 9 Poster Flash Talks 11 to 19 (10 x 3 min) Attendees: 128 |
POSTPONED |
SESSION 8 Academia-Industry Cooperation |
POSTPONED |
SESSION 10 Management Committee Meeting |
Time (CET) |
Event - Day 3 |
9:00 - 10:40 |
SESSION 12 (join here) WG4 (chair: Nuska Tschammer) 9:00-9:50 Martin J. Lohse (MDC, Berlin; ISAR Bioscience Institute, Munich) Watching receptors at work – using the microscope to study GPCRs 9:50-10:10 Bence Szalai (University of Semmelweis) Gene expression signatures - footprints of GPCR signalling pathway activity Short talks (selected from abstracts) 10:10-10:25 Adrian Morales-Pastor (Pompeu Fabra University) Exploration of allosteric communication networks that underlie GPCR functionality 10:25-10:40 Tõnis Laasfeld (University of Tartu) Novel fluorescence ligands for the characterization of muscarinic acetylcholine receptors Attendees: 139 |
10:40 - 11:15 |
BREAK (35 min) |
11:15 - 12:30 |
SESSION 13 (join here) WG5 (chair: Jana Selent) 11:15-11:45 Vassiliki Iconomidou & Avgi-Elena Apostolakou (University of Athens) hGPCRnet: A tool for Cell-Type Specifc Analysis of GPCR Signaling Pathways 11:45-12:10 GPCRdb update (David Gloriam) 12:10-12:30 GPCRmd update (Mariona Torrens-Fontanals) Attendees: 118 |
12:30 - 12:45 |
BREAK (15 min) |
12:45 - 13:45 |
SESSION 14 (join here) Short talks (chair: David Gloriam) 12:45-13:00 Alexey Bondar (Augusta University) Membrane domain localization and mobility of Gs signaling cascade components 13:00-13:15 Marcel Bermudez (Freie Universität Berlin) Dynamic pharmacophores unveil binding mode ensembles of partial GPCR agonists 13:15-13:30 Pascale Crépieux (Université de Tours) Pharmacological approaches to decipher the signaling networks of GPCR of the reproductive axis 13:30-13:45 Shannon O’Brien (University of Birmingham) Hydroxy-carboxylic acid receptor 2 signalling at endosomal compartments Attendees: 110 |
13:45 - 14:00 |
BREAK (15 min) |
14:00 |
|
15:00-17:00 |
SESSION 16: We're not saying Goodbye. We're saying, see you soon! (join here) Meeting up in virtual rooms. Moderators: Room 1: Jana Selent Room 2: Martha Sommer Room 3: Antonella Di Pizio Room 4: Marcel Bermudez Room 5: Necla Birgul Attendees: 35 |
POSTPONED |
Focus Group on Functional Selectivity (by invitation only) Organizer: Peter Kolb |
Dear participants,
Each meeting session contains a clickable join here-link within the online program. Clicking on the link will take you directly to the session in the Zoom app.
Zoom will ask you for a password. Please enter the password you received via email from us. If you cannot find this email/password, please send a password request to ernest.ca18133@gmail.com.
If you experience technical problems accessing the online sessions:
Check out the instructions here.
If you can't figure out the problem yourself, please contact the Conference Manager Luise Wagner (conference.ictac@gmail.com) or the conference hotline:
Phone (Spain): +34 641-824-596
Phone (US and Canada): +1 778-807-1732
Each meeting session contains a clickable join here-link within the online program. Clicking on the link will take you directly to the session in the Zoom app.
Zoom will ask you for a password. Please enter the password you received via email from us. If you cannot find this email/password, please send a password request to ernest.ca18133@gmail.com.
If you experience technical problems accessing the online sessions:
Check out the instructions here.
If you can't figure out the problem yourself, please contact the Conference Manager Luise Wagner (conference.ictac@gmail.com) or the conference hotline:
Phone (Spain): +34 641-824-596
Phone (US and Canada): +1 778-807-1732
